Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | APAF1 | O14727 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL145356 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL145357 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL29349411 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2409472 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL10035965 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6426499 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL29362921 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL9192803 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9015126 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL7697694 | 0.90 | MEN1 (0.81) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263590-B1 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS CO (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1263590-A2 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | Kodak Polychrome Graphics Company Ltd. (US) | 2002-12-11 | — | — | EP | claimed |
| US-6352811-B1 | POSITIVE-WORKING THERMAL IMAGING ELEMENT COMPRISING SUBSTRATE, THERMALLY SENSITIVE COMPOSITE STRUCTURE HAVING FIRST LAYER OF POLYMER WHICH IS SOLUBLE OR DISPERSIBLE IN AQUEOUS SOLUTION AND SOLUBILITY INHIBITOR, SECOND LAYER OF INSOLUBLE POLYMER | KODAK POLYCHROME GRAPHICS LLC | 2002-03-05 | — | — | US | claimed |
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | claimed |
| WO-2001045958-A2 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS COMPANY LTD (US) | 2001-06-28 | — | — | WO | claimed |
| US-7279263-B2 | Dual-wavelength positive-working radiation-sensitive elements | KODAK GRAPHIC COMMUNICATIONS CANADA COMPANY (CA) | 2007-10-09 | — | — | US | disclosed |
| US-20050287468-A1 | Dual-wavelength positive-working radiation-sensitive elements | KODAK GRAPHIC COMMUNICATIONS CANADA COMPANY (CA) | 2005-12-29 | — | — | US | disclosed |
| EP-1542871-A1 | METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA | Creo SRL (CA) | 2005-06-22 | — | — | EP | disclosed |
| US-6905812-B2 | Positive working; heat sensitive element; phenol-formaldehyde resin | KODAK POLYCHROME GRAPHICS LLC (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1263590-B1 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS CO (US) | 2005-03-16 | — | — | EP | disclosed |
| US-6739260-B2 | Method for the preparation of a negative working printing plate | AGFA-GEVAERT (BE) | 2004-05-25 | — | — | US | disclosed |
| US-20040038152-A1 | Method for making printing plate by inkjet deposition on positive-working media | CREO SRL (CA) | 2004-02-26 | — | — | US | disclosed |
| EP-1123212-B1 | METHOD FOR MANUFACTURE OF ELECTRONIC PARTS | KODAK POLYCHROME GRAPHICS CO (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0887182-B1 | Heat-sensitive composition for making a lithographic printing form precursor | KODAK POLYCHROME GRAPHICS CO (US) | 2002-07-24 | — | — | EP | disclosed |
| US-6423456-B1 | COATING WITH HEAT SENSITIVE AQUEOUS DEVELOPER COMPRISING VINYLPHENOL DERIVATIVE-(HYDROXY)ALKYL (METH)ACRYLATE COPOLYMER; PRINTED CIRCUITS | KODAK POLYCHROME GRAPHICS LLC | 2002-07-23 | — | — | US | disclosed |
| US-20020045124-A1 | Aqueous developer soluble polymer, such as a phenolic resin; a compound that reduces the aqueous developer solubility of the polymer such as quaternized nitrogen atom, such as quinolinium compounds and benzothiazolium compounds | LASER PACIFIC MEDIA CORPORATION | 2002-04-18 | — | — | US | disclosed |
| US-6352811-B1 | POSITIVE-WORKING THERMAL IMAGING ELEMENT COMPRISING SUBSTRATE, THERMALLY SENSITIVE COMPOSITE STRUCTURE HAVING FIRST LAYER OF POLYMER WHICH IS SOLUBLE OR DISPERSIBLE IN AQUEOUS SOLUTION AND SOLUBILITY INHIBITOR, SECOND LAYER OF INSOLUBLE POLYMER | KODAK POLYCHROME GRAPHICS LLC | 2002-03-05 | — | — | US | disclosed |
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | disclosed |
| EP-0825927-B1 | LITHOGRAPHIC PRINTING FORM PRECURSOR AND ITS USE BY HEAT IMAGING | KODAK POLYCHROME GRAPHICS CO (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0930539-A1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1999-07-21 | — | — | EP | disclosed |