Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | APAF1 | O14727 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | PLA2G1B | P04054 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 1/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL145356 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL5500973 | 1.00 | MEN1 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL29349411 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2409472 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL10035965 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6426499 | 0.99 | NSD2 (1.00) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL29362921 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Bromide SCHEMBL9192803 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9015126 | 0.98 | NSD2 (0.98) | MEN1KMT2AHTTNPC1RAB9A | |
| Iodide SCHEMBL7697694 | 0.90 | MEN1 (0.81) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149190-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | The Johns Hopkins University (US) | 2017-04-05 | — | — | EP | claimed |
| US-20170058314-A1 | NOVEL METHODOLOGY FOR IDENTIFYING ANTI-PERSISTER ACTIVITY AND ANTIMICROBIAL SUSCEPTIBILITY FOR BORRELIA BURGDORFERI AND OTHER BACTERIA | ZHANG YING (US) | 2017-03-02 | — | — | US | claimed |
| WO-2015171225-A1 | IDENTIFICATION OF NOVEL ANTI-PERSISTER ACTIVITY FOR BORRELIA BURGDORFERI | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | claimed |
| EP-1263590-B1 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS CO (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1263590-A2 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | Kodak Polychrome Graphics Company Ltd. (US) | 2002-12-11 | — | — | EP | claimed |
| US-6352811-B1 | POSITIVE-WORKING THERMAL IMAGING ELEMENT COMPRISING SUBSTRATE, THERMALLY SENSITIVE COMPOSITE STRUCTURE HAVING FIRST LAYER OF POLYMER WHICH IS SOLUBLE OR DISPERSIBLE IN AQUEOUS SOLUTION AND SOLUBILITY INHIBITOR, SECOND LAYER OF INSOLUBLE POLYMER | KODAK POLYCHROME GRAPHICS LLC | 2002-03-05 | — | — | US | claimed |
| US-6342329-B1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2002-01-29 | — | — | US | claimed |
| WO-2001045958-A2 | THERMALLY IMAGEABLE ELEMENT AND LITHOGRAPHIC PRINTING PLATE | KODAK POLYCHROME GRAPHICS COMPANY LTD (US) | 2001-06-28 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| EP-0930539-A1 | Image-forming medium | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 1999-07-21 | — | — | EP | claimed |
| US-4728796-A | Method for ionization of polymers | MEDICAL COLLEGE OF WISCONSIN (US) | 1988-03-01 | — | — | US | claimed |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | Didenko, Kirill (US) | 2025-07-03 | — | — | US | disclosed |
| EP-3478792-B1 | CHEMILUMINESCENT SUBSTRATES | BECKMAN COULTER INC (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023187599-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | DIDENKO KIRILL (MX) | 2023-10-05 | — | — | WO | disclosed |
| US-20230150960-A1 | COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA | UNIV JEFFERSON (US) | 2023-05-18 | — | — | US | disclosed |
| EP-0819119-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1997026245-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR GENERATING CHEMILUMINESCENCE WITH PHOSPHATASE ENZYMES | LUMIGEN, INC. (US) | 1997-07-24 | — | — | WO | disclosed |
| US-4728796-A | Method for ionization of polymers | MEDICAL COLLEGE OF WISCONSIN (US) | 1988-03-01 | — | — | US | disclosed |
| US-4030927-A | PHOTOGRAPHIC SILVER HALIDE EMULSIONS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-21 | — | — | US | disclosed |
| US-RE29255-E | Photographic layers containing perfluoro compounds and coating thereof | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150960-A1 | COMPOSITIONS AND METHODS OF USING CYANINE DYES TO TARGET CANCER AND MITOCHONDRIA | TFAM, COX5A, UQCRC1 | MEN1 2633/4885KMT2A 3675/4885HTT 2179/4885 |
| US-20250213601-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES | ACE2, FURIN, SARS1 | MEN1 732/4885KMT2A 2058/4885HTT 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.