Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699353 | 0.85 | HDAC4 (0.50) | POLBMAPTSMN1; SMN2HDAC4MAPK1 | |
| SCHEMBL7701529 | 0.83 | POLB (0.52) | POLBMAPTKDM4ESMN1; SMN2FAAH | |
| SCHEMBL7700043 | 0.81 | TACR1 (0.49) | HDAC4 | |
| SCHEMBL7696235 | 0.81 | KMT2A (0.46) | POLBMAPTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7703284 | 0.81 | EPHX2 (0.46) | MAPTHDAC4 | |
| SCHEMBL7699835 | 0.78 | IKBKB (0.42) | MAPTKDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL7697065 | 0.77 | FAAH (0.52) | POLBMAPTKDM4ESMN1; SMN2FAAH | |
| SCHEMBL7700999 | 0.76 | MAPT (0.48) | POLBMAPTKDM4EHSD17B10LMNA | |
| SCHEMBL7695161 | 0.75 | IKBKB (0.50) | MAPTKDM4EHSD17B10ALDH1A1HDAC4 | |
| SCHEMBL7694290 | 0.75 | TACR1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |