Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700999 | 0.91 | MAPT (0.48) | HDAC4GSK3BMAPTPOLBROCK2 | |
| SCHEMBL7700043 | 0.91 | TACR1 (0.49) | HDAC4DGAT1 | |
| SCHEMBL7703284 | 0.88 | EPHX2 (0.46) | HDAC4GSK3BMAPTROCK2PRKCG | |
| SCHEMBL7697933 | 0.85 | POLB (0.50) | HDAC4MAPTPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL7694290 | 0.84 | TACR1 (0.51) | — | |
| SCHEMBL7699835 | 0.83 | IKBKB (0.42) | HDAC4GSK3BHDAC6MAPTDGAT1 | |
| SCHEMBL7696355 | 0.83 | MAPT (0.46) | HDAC4GSK3BMAPTPOLBMAP4K4 | |
| SCHEMBL7695161 | 0.82 | IKBKB (0.50) | HDAC4HDAC6MAPTDGAT1KDM1A | |
| SCHEMBL7698726 | 0.82 | LMNA (0.47) | GSK3BMAPTPOLBROCK2MAP4K4 | |
| SCHEMBL27189073 | 0.81 | DGAT1 (0.49) | HDAC4GSK3BHDAC6DGAT1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |