Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697491 | 0.84 | HDAC4 (0.49) | TRPV1MAPTHDAC4RXFP1DGAT1 | |
| SCHEMBL7701281 | 0.84 | MAPT (0.49) | KMT2AKDM4EMEN1RAB9ANPC1 | |
| SCHEMBL7704094 | 0.84 | MAPT (0.44) | KMT2AKDM4EMEN1RAB9ANPC1 | |
| SCHEMBL7697933 | 0.81 | POLB (0.50) | KDM4ESMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL7693843 | 0.81 | TRPV1 (0.47) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7701100 | 0.80 | DGAT1 (0.51) | KMT2AKDM4EMEN1RAB9ANPC1 | |
| SCHEMBL7695533 | 0.80 | ADCY8 (0.47) | KDM4EMAPTADCY8ADCY1HDAC4 | |
| SCHEMBL7694280 | 0.78 | KDM4E (0.59) | KMT2AKDM4EMEN1RAB9ANPC1 | |
| SCHEMBL7695161 | 0.77 | IKBKB (0.50) | KDM4EMAPTHSD17B10HDAC4RXFP1 | |
| SCHEMBL7702798 | 0.76 | MAPT (0.50) | KDM4ERAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |