Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701897 | 0.88 | KDM4E (0.55) | MAPTALDH1A1SMN1; SMN2GAANPC1 | |
| SCHEMBL7695065 | 0.87 | NPC1 (0.55) | MAPTTP53ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7701071 | 0.87 | TSHR (0.63) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7693959 | 0.86 | MAPT (0.52) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7695332 | 0.84 | NPC1 (0.56) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7701450 | 0.81 | EPHX2 (0.48) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7696209 | 0.81 | KDM4E (0.55) | MAPTTP53ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7695319 | 0.81 | MAPT (0.57) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7701088 | 0.81 | MAPT (0.53) | MAPTPOLBTP53SMN1; SMN2GAA | |
| SCHEMBL7704976 | 0.81 | MAPT (0.61) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |