Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695319 | 0.89 | MAPT (0.57) | KDM4EGAAHPGDHTTTDP1 | |
| SCHEMBL7701088 | 0.88 | MAPT (0.53) | KDM4EGAAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL7697940 | 0.88 | MAPT (0.57) | KDM4EGAALMNAHPGDHTT | |
| SCHEMBL7704976 | 0.88 | MAPT (0.61) | KDM4EGAAHPGDMAPTRAB9A | |
| SCHEMBL3128951 | 0.87 | IKBKB (0.54) | KDM4EGAALMNAHPGDHTT | |
| SCHEMBL7700032 | 0.86 | NPC1 (0.55) | KDM4EGAALMNAHPGDHTT | |
| SCHEMBL7703322 | 0.85 | KDM4E (0.72) | KDM4EGAAHPGDTDP1MAPT | |
| SCHEMBL7696209 | 0.84 | KDM4E (0.55) | KDM4EGAALMNAHPGDHTT | |
| SCHEMBL7693588 | 0.83 | KDM4E (0.65) | KDM4EGAALMNAHPGDTDP1 | |
| SCHEMBL7699504 | 0.83 | MAPT (0.55) | KDM4ELMNAHPGDHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |