Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMO | Q99835 | 4/20 | 0.54 |
| ▸ | STAT1 | P42224 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697462 | 0.86 | MAPT (0.59) | KDM4EGAASMONPC1RAB9A | |
| SCHEMBL7705439 | 0.86 | KDM4E (0.50) | KDM4EGAASMOSTAT1NPC1 | |
| SCHEMBL7701897 | 0.84 | KDM4E (0.55) | KDM4EGAANPC1RAB9AHPGD | |
| SCHEMBL7693588 | 0.83 | KDM4E (0.65) | KDM4EGAASMONPC1RAB9A | |
| SCHEMBL7697940 | 0.81 | MAPT (0.57) | KDM4EGAANPC1RAB9AHPGD | |
| SCHEMBL7699225 | 0.81 | PTGES (0.53) | SMO | |
| SCHEMBL7703221 | 0.80 | RAB9A (0.67) | KDM4EGAANPC1RAB9AHPGD | |
| SCHEMBL7699800 | 0.80 | RAB9A (0.67) | KDM4EGAANPC1RAB9AHPGD | |
| SCHEMBL7695319 | 0.80 | MAPT (0.57) | KDM4EGAANPC1RAB9AHPGD | |
| SCHEMBL7701088 | 0.79 | MAPT (0.53) | KDM4EGAAMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |