Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701897 | 0.88 | KDM4E (0.55) | MAPTSMN1; SMN2KDM4EGAARXFP1 | |
| SCHEMBL7695319 | 0.86 | MAPT (0.57) | MAPTTP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL7704976 | 0.85 | MAPT (0.61) | MAPTTP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL7699501 | 0.84 | MAPT (0.55) | MAPTDGAT1POLB | |
| SCHEMBL7701962 | 0.82 | TAOK1 (0.54) | MAPTTP53SMN1; SMN2DGAT1POLB | |
| SCHEMBL7703221 | 0.82 | RAB9A (0.67) | MAPTTP53SMN1; SMN2DGAT1KDM4E | |
| SCHEMBL7697940 | 0.81 | MAPT (0.57) | MAPTTP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL7693588 | 0.81 | KDM4E (0.65) | MAPTTP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL7701405 | 0.80 | NPC1 (0.56) | MAPTTP53SMN1; SMN2DGAT1POLB | |
| SCHEMBL12829331 | 0.80 | NR1H4 (0.73) | MAPTTP53SMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |