Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701714 | 0.89 | CHRM5 (0.49) | CHRM5HTR7TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4740625 | 0.84 | LMNA (0.57) | ALDH1A1LMNAHTTMAPTCYP2C19 | |
| SCHEMBL4741043 | 0.83 | KMT2A (0.58) | ALDH1A1LMNAHTTGAAMAPT | |
| SCHEMBL7700065 | 0.83 | AKR1C3 (0.66) | ALDH1A1NPSR1LMNATP53HTT | |
| SCHEMBL7694604 | 0.79 | ALDH1A1 (0.77) | ALDH1A1NPSR1LMNATP53HTT | |
| SCHEMBL21511531 | 0.79 | ALDH1A1 (0.47) | HTR7TMEM97SIGMAR1ALDH1A1NPSR1 | |
| SCHEMBL5093207 | 0.78 | PKM (0.47) | CHRM5HTR7TMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4739877 | 0.77 | TSHR (0.50) | HTTGAACYP2C19RAB9A | |
| SCHEMBL15010154 | 0.77 | KMT2A (0.70) | ALDH1A1NPSR1LMNAHTTPKM | |
| SCHEMBL4541355 | 0.76 | USP2 (0.53) | CHRM5ALDH1A1LMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020015-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-03-14 | — | — | WO | disclosed |