Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741097 | 0.85 | ALDH1A1 (0.51) | TSHRCYP19A1CYP3A4CYP2C19RAB9A | |
| SCHEMBL4740459 | 0.85 | ALDH1A1 (0.51) | TSHRCYP19A1CYP3A4CYP2C19RAB9A | |
| SCHEMBL4741043 | 0.85 | KMT2A (0.58) | CYP19A1CYP3A4CYP2C19GAAHTT | |
| SCHEMBL4740625 | 0.82 | LMNA (0.57) | TSHRCYP3A4CYP2C19L3MBTL1HTT | |
| SCHEMBL643115 | 0.78 | HTR7 (0.60) | TSHRCYP3A4CYP2C19L3MBTL1GAA | |
| SCHEMBL4741083 | 0.78 | TSHR (0.58) | TSHRAKR1C3AKR1C1KMT2AKDM4E | |
| SCHEMBL7697945 | 0.77 | CHRM5 (0.51) | CYP2C19RAB9AGAAHTT | |
| SCHEMBL4739879 | 0.77 | RAB9A (0.58) | RAB9AGAAHTTMEN1KMT2A | |
| SCHEMBL5500815 | 0.77 | AKR1C3 (0.41) | TSHRCYP19A1CYP3A4CYP2C19RAB9A | |
| SCHEMBL4740463 | 0.77 | TSHR (0.56) | TSHRAKR1C3AKR1C1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |