Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427343 | 0.91 | POLB (0.60) | POLBKMT2AALDH1A1GAAMAPT | |
| SCHEMBL4481252 | 0.87 | ALDH1A1 (0.74) | POLBKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL13919544 | 0.87 | ALDH1A1 (0.74) | POLBKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL18262723 | 0.87 | KMT2A (0.77) | POLBKMT2AALDH1A1GAAMAPT | |
| SCHEMBL18262720 | 0.87 | KMT2A (0.77) | POLBKMT2AALDH1A1GAAMAPT | |
| SCHEMBL11316794 | 0.85 | KMT2A (1.00) | POLBKMT2AALDH1A1GAAMAPT | |
| SCHEMBL21914922 | 0.84 | KMT2A (0.65) | POLBKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL20246861 | 0.84 | ALDH1A1 (0.82) | POLBKMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL4861809 | 0.83 | ALDH1A1 (1.00) | POLBKMT2AALDH1A1GAAMAPT | |
| SCHEMBL392680 | 0.83 | ALDH1A1 (1.00) | POLBKMT2AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024631-A1 | PROCESS TO PREPARE (2S)-2-(DIPROPYLAMINO)-6-ETHOXY-2,3-DIHYDRO-1H-INDENE-5-CARBOXAMIDE | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |