Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701990 | 0.87 | IKBKB (0.46) | IKBKBHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7693745 | 0.81 | IKBKB (0.53) | IKBKBHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7700875 | 0.80 | MEN1 (0.56) | TP53MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7697060 | 0.80 | IKBKB (0.40) | IKBKBHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7700016 | 0.77 | IKBKB (0.42) | IKBKBTRPV1MAPTMEN1KMT2A | |
| SCHEMBL7699623 | 0.77 | AVPR2 (0.46) | TP53MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7695134 | 0.76 | L3MBTL1 (0.48) | IKBKBTRPV1TP53MAPTMEN1 | |
| SCHEMBL7694392 | 0.75 | TARBP2 (0.51) | IKBKBTP53MAPTALDH1A1KMT2A | |
| SCHEMBL7699252 | 0.75 | IKBKB (0.39) | IKBKBHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7698666 | 0.74 | L3MBTL1 (0.44) | IKBKBMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |