Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692116 | 0.85 | DHPS (0.55) | CA12CA9ALDH1A1CHRM1CASP3 | |
| SCHEMBL30059278 | 0.81 | NPC1 (0.52) | CA12CA9CHRM1MAPTRAB9A | |
| SCHEMBL20324958 | 0.78 | MAPT (0.50) | CA12CA9CHRM1MAPTRAB9A | |
| SCHEMBL15757029 | 0.78 | CHRM1 (0.47) | ALDH1A1CHRM1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12204885 | 0.78 | CHRM1 (0.50) | CHRM1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14353465 | 0.78 | PDE10A (0.53) | CHRM1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21162380 | 0.77 | NPC1 (0.55) | CA12CA9CHRM1MAPTRAB9A | |
| SCHEMBL29427924 | 0.77 | ALOX15 (0.65) | ALDH1A1CASP3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL741365 | 0.77 | ALOX15 (0.65) | ALDH1A1CASP3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30058616 | 0.77 | NPC1 (0.55) | CA12CA9CHRM1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002018381-A1 | 6,7-DIHYDRO-PYRROLO[3,4-B]PYRIDIN-5-ONES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-03-07 | — | — | WO | claimed |
| WO-2002018381-A1 | 6,7-DIHYDRO-PYRROLO[3,4-B]PYRIDIN-5-ONES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2002-03-07 | — | — | WO | disclosed |