Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701239 | 0.91 | MAPT (0.60) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7699719 | 0.90 | MAPT (0.46) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL7698114 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7699148 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7699604 | 0.81 | MAPT (0.47) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7701479 | 0.81 | HSP90AA1 (0.54) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7695132 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7699621 | 0.80 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7699090 | 0.80 | MAPT (0.40) | MAPTALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL7694375 | 0.80 | HSD17B10 (0.40) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |