Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698104 | 0.91 | MAPT (0.51) | MAPTALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL7699719 | 0.90 | MAPT (0.46) | MAPTALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL7701479 | 0.87 | HSP90AA1 (0.54) | MAPTALDH1A1KDM4ELMNARXFP1 | |
| SCHEMBL7698114 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ELMNARXFP1 | |
| SCHEMBL7699604 | 0.81 | MAPT (0.47) | MAPTALDH1A1KDM4ELMNARXFP1 | |
| SCHEMBL7695132 | 0.80 | MAPT (0.49) | MAPTALDH1A1KDM4ELMNARXFP1 | |
| SCHEMBL7701387 | 0.80 | MAPT (0.69) | MAPTALDH1A1KDM4ELMNARXFP1 | |
| SCHEMBL7695678 | 0.80 | CHRNB2 (0.49) | MAPTALDH1A1KDM4ELMNATSHR | |
| SCHEMBL7694375 | 0.80 | HSD17B10 (0.40) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL7699090 | 0.80 | MAPT (0.40) | MAPTALDH1A1KDM4ELMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |