Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 10/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21218948 | 0.79 | MMP2 (0.49) | ERAP2ERAP1LNPEPLTA4HMMP2 | |
| SCHEMBL7698452 | 0.76 | NOS2 (0.48) | NOS2 | |
| SCHEMBL6510267 | 0.72 | LTA4H (0.39) | LTA4HMMP2MMP9 | |
| SCHEMBL9277060 | 0.71 | HTT (0.52) | MMP2MMP9 | |
| SCHEMBL9277064 | 0.71 | HTT (0.52) | MMP2MMP9 | |
| SCHEMBL1558756 | 0.71 | BRAF (0.65) | NOS2 | |
| SCHEMBL8199077 | 0.71 | BRAF (0.51) | NOS2 | |
| SCHEMBL6394247 | 0.71 | BRAF (0.51) | NOS2 | |
| SCHEMBL13753817 | 0.70 | HPGD (0.52) | NOS2 | |
| SCHEMBL7293578 | 0.69 | MMP2 (0.56) | ERAP2ERAP1LNPEPLTA4HMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |