Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ARAF | P10398 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199077 | 0.83 | BRAF (0.51) | NOS2RAF1ARAFBRAFHDAC1 | |
| SCHEMBL6394247 | 0.80 | BRAF (0.51) | NOS2RAF1ARAFBRAFHDAC1 | |
| SCHEMBL1558756 | 0.80 | BRAF (0.65) | NOS2RAF1ARAFBRAFHDAC1 | |
| SCHEMBL13753817 | 0.79 | HPGD (0.52) | NOS2RAF1ARAFBRAFHDAC1 | |
| SCHEMBL7698671 | 0.77 | KEAP1 (0.54) | BRAFHDAC1ALDH1A1 | |
| SCHEMBL11026476 | 0.77 | NOS2 (0.62) | NOS2RAF1ARAFBRAFHDAC1 | |
| SCHEMBL267307 | 0.76 | KDM4E (0.62) | NOS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7698207 | 0.76 | ERAP2 (0.46) | NOS2 | |
| SCHEMBL13958731 | 0.76 | ALDH1A1 (0.49) | NOS2RAF1ARAFBRAFHDAC1 | |
| Hydrochloric Acid SCHEMBL5100210 | 0.74 | ALDH1A1 (0.60) | NOS2KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |