Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891994 | 0.77 | KIF11 (0.46) | MEN1KMT2AMAPTKIF11KDM4E | |
| SCHEMBL7679735 | 0.77 | KIF11 (0.46) | MEN1KMT2AKIF11KDM4E | |
| SCHEMBL892668 | 0.77 | CYP2C9 (0.47) | ALDH1A1MEN1KMT2AKIF11KDM4E | |
| SCHEMBL30532272 | 0.77 | CYP2C9 (0.47) | ALDH1A1MEN1KMT2AKIF11KDM4E | |
| SCHEMBL25366837 | 0.74 | CCNB2 (0.43) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL30642000 | 0.74 | CCNB2 (0.43) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL15313180 | 0.73 | KIF11 (0.43) | MEN1KMT2AKIF11DDR1KDM4E | |
| SCHEMBL14074159 | 0.68 | MAPT (0.57) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL8665875 | 0.68 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7957008 | 0.67 | ADRA1D (0.62) | ALDH1A1KMT2AMAPTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-1070716-A1 | Beta-carboline derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-01-24 | — | — | EP | disclosed |