Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392781 | 0.85 | KMT2A (0.62) | TSHR | |
| SCHEMBL195152 | 0.83 | CA2 (0.55) | L3MBTL1 | |
| SCHEMBL7408363 | 0.82 | CYP19A1 (0.47) | HDAC3HDAC1HDAC2HDAC6POLB | |
| SCHEMBL893242 | 0.81 | KMT2A (0.60) | TSHRPTPN1 | |
| SCHEMBL894410 | 0.80 | KMT2A (0.59) | TSHRPTPN1 | |
| SCHEMBL7399025 | 0.78 | KMT2A (0.43) | PTPN1 | |
| SCHEMBL10680125 | 0.77 | L3MBTL1 (0.55) | PTPN1L3MBTL1 | |
| SCHEMBL7970997 | 0.76 | CXCR4 (0.69) | HDAC3HDAC2HDAC6GRIN1GRIN2A | |
| SCHEMBL28367131 | 0.75 | ALDH1A1 (0.55) | KDM4E | |
| SCHEMBL24990193 | 0.73 | CA2 (0.59) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |