Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028418 | 0.79 | KMT2A (0.70) | KMT2AMEN1NPY5RALDH1A1POLB | |
| SCHEMBL5028416 | 0.79 | KMT2A (0.70) | KMT2AMEN1NPY5RALDH1A1POLB | |
| SCHEMBL5025740 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1GAACYP2C9 | |
| SCHEMBL5025742 | 0.79 | KMT2A (0.56) | KMT2AMEN1ALDH1A1GAACYP2C9 | |
| SCHEMBL7698607 | 0.75 | KMT2A (0.58) | KMT2AMEN1NPY5RALDH1A1GAA | |
| SCHEMBL5025754 | 0.73 | MEN1 (0.60) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5025758 | 0.73 | MEN1 (0.60) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7700849 | 0.72 | ALDH1A1 (0.72) | KMT2AMEN1NPY5RALDH1A1POLB | |
| SCHEMBL7697188 | 0.72 | NPY5R (0.67) | KMT2AMEN1NPY5RALDH1A1POLB | |
| SCHEMBL7702562 | 0.71 | NPY5R (0.61) | KMT2AMEN1NPY5RALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057220-A1 | HYDRAZIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |