Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697962 | 0.89 | L3MBTL1 (0.56) | POLBKDM4EALDH1A1TDP1DGAT1 | |
| SCHEMBL7699968 | 0.87 | ATM (0.49) | LMNAHTTPOLBKDM4EALDH1A1 | |
| SCHEMBL7695134 | 0.85 | L3MBTL1 (0.48) | KDM4EDGAT1GAAHSD17B10L3MBTL1 | |
| SCHEMBL7699994 | 0.81 | ATM (0.47) | LMNAHTTPOLBALDH1A1GAA | |
| SCHEMBL7703324 | 0.79 | L3MBTL1 (0.53) | POLBKDM4EALDH1A1DGAT1GAA | |
| SCHEMBL7693997 | 0.79 | ATM (0.47) | LMNAHTTPOLBKDM4EALDH1A1 | |
| SCHEMBL7696391 | 0.79 | MAPT (0.54) | HTTKDM4EALDH1A1DGAT1SMN1; SMN2 | |
| SCHEMBL7699897 | 0.79 | L3MBTL1 (0.51) | LMNAALDH1A1DGAT1GAASMN1; SMN2 | |
| SCHEMBL7695332 | 0.78 | NPC1 (0.56) | LMNAHTTPOLBKDM4EALDH1A1 | |
| SCHEMBL7695366 | 0.78 | USP2 (0.56) | LMNAHTTKDM4EALDH1A1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |