Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697962 | 0.89 | L3MBTL1 (0.56) | L3MBTL1NPC1RAB9APOLBDGAT1 | |
| SCHEMBL7699467 | 0.88 | ALDH1A1 (0.52) | L3MBTL1NPC1RAB9ADGAT1MAPT | |
| SCHEMBL7696391 | 0.87 | MAPT (0.54) | L3MBTL1NPC1RAB9ADGAT1MAPT | |
| SCHEMBL7695331 | 0.85 | USP2 (0.57) | L3MBTL1NPC1RAB9APOLBDGAT1 | |
| SCHEMBL7699504 | 0.84 | MAPT (0.55) | L3MBTL1NPC1RAB9ADGAT1MAPT | |
| SCHEMBL7699897 | 0.84 | L3MBTL1 (0.51) | L3MBTL1RAB9ADGAT1MAPTALDH1A1 | |
| SCHEMBL7701960 | 0.84 | DGAT1 (0.52) | L3MBTL1DGAT1MAPTALDH1A1GAA | |
| SCHEMBL7701794 | 0.84 | SMN1; SMN2 (0.53) | L3MBTL1NPC1RAB9APOLBDGAT1 | |
| SCHEMBL7703296 | 0.83 | DGAT1 (0.51) | L3MBTL1NPC1RAB9APOLBDGAT1 | |
| SCHEMBL7698228 | 0.83 | MAPT (0.56) | L3MBTL1NPC1RAB9APOLBDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |