Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699968 | 0.94 | ATM (0.49) | ATMKMT2AMEN1MAPK1MAPT | |
| SCHEMBL7703801 | 0.89 | L3MBTL1 (0.49) | KMT2AMEN1MAPTTP53TSHR | |
| SCHEMBL7693997 | 0.82 | ATM (0.47) | ATMKMT2AMEN1MAPK1MAPT | |
| SCHEMBL7696382 | 0.82 | L3MBTL1 (0.58) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7698707 | 0.81 | LMNA (0.53) | ATMKMT2AMEN1MAPK1MAPT | |
| SCHEMBL7694348 | 0.79 | HTR2C (0.38) | KMT2AMEN1MAPTTP53SMN1; SMN2 | |
| SCHEMBL7698990 | 0.79 | HTR2C (0.43) | KMT2AMEN1TP53SMN1; SMN2LMNA | |
| SCHEMBL7699217 | 0.78 | MAPT (0.36) | KMT2AMEN1MAPK1MAPTTP53 | |
| SCHEMBL7701523 | 0.76 | L3MBTL1 (0.49) | KMT2AMEN1MAPK1MAPTTP53 | |
| SCHEMBL7695160 | 0.74 | MAPT (0.41) | KMT2AMEN1MAPK1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |