Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209387 | 0.84 | PTGDR2 (0.74) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL9585134 | 0.76 | PTGDR2 (0.49) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL13802422 | 0.74 | PTGDR2 (0.76) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL4270126 | 0.73 | THRA (0.71) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL1322507 | 0.73 | LMNA (1.00) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL9584740 | 0.73 | TP53 (0.56) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL8167328 | 0.73 | MEN1 (0.52) | ALDH1A1MEN1LMNAKMT2APTGDR2 | |
| SCHEMBL4211522 | 0.72 | PTGDR2 (0.72) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL11459495 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MEN1LMNAKMT2ACYP1A2 | |
| SCHEMBL4266132 | 0.72 | FOLH1 (0.63) | ALDH1A1MEN1LMNAKMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |