Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971900 | 0.86 | CHRNB2 (0.38) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL7221029 | 0.82 | CHRNB2 (0.36) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL7699063 | 0.78 | CHRNB2 (0.34) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL7700183 | 0.78 | CHRNB2 (0.33) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL7697700 | 0.77 | GRM5 (0.41) | CHRNB2CHRNA4PDE4APDE4BPDE4C | |
| SCHEMBL17507209 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL16115777 | 0.77 | — | — | |
| SCHEMBL16115008 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL16135495 | 0.77 | — | — | |
| SCHEMBL7698407 | 0.77 | CHRNB2 (0.36) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057263-A1 | 8-AZABICYCLO \"3.2.1.! OCTANES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |