Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 8/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698935 | 0.86 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3CYP11B1 | |
| SCHEMBL7230387 | 0.81 | KMT2A (0.40) | CHRNB2CHRNA4KMT2ACHRNB4CHRNA3 | |
| SCHEMBL16115777 | 0.80 | — | — | |
| SCHEMBL17940856 | 0.80 | KDM4E (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL16135470 | 0.80 | CHRNB4 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CYP11B1 | |
| SCHEMBL16115008 | 0.80 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CYP11B1 | |
| SCHEMBL17507209 | 0.80 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CYP11B1 | |
| SCHEMBL16135495 | 0.80 | — | — | |
| SCHEMBL7698407 | 0.80 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CYP11B1 | |
| SCHEMBL16565778 | 0.80 | KDM4E (0.31) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294545-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1033914-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026478-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |