Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL7694429 | 0.99 | MAPT (0.80) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3760191 | 0.90 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL6827361 | 0.80 | HTR6 (0.61) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL6829461 | 0.79 | HTR6 (0.60) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7663455 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3766151 | 0.78 | TP53 (0.91) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7669974 | 0.76 | ALDH1A1 (0.84) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7669890 | 0.74 | ALDH1A1 (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7665352 | 0.72 | ALDH1A1 (0.84) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL3756887 | 0.72 | TP53 (1.00) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |