Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669051 | 0.86 | HTR6 (0.78) | TP53ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL7663455 | 0.84 | ALDH1A1 (1.00) | TP53ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7669974 | 0.80 | ALDH1A1 (0.84) | TP53ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3755285 | 0.78 | L3MBTL1 (0.81) | TP53ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7665352 | 0.77 | ALDH1A1 (0.84) | TP53ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7669890 | 0.77 | ALDH1A1 (1.00) | TP53ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7674392 | 0.77 | POLB (0.84) | TP53ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7669650 | 0.77 | POLB (0.81) | TP53ALDH1A1MEN1KMT2APLA2G1B | |
| SCHEMBL3760191 | 0.74 | MAPT (1.00) | TP53ALDH1A1MEN1KMT2APLA2G1B | |
| SCHEMBL3756898 | 0.74 | POLB (0.84) | TP53ALDH1A1MEN1KMT2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | claimed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | claimed |
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-8394788-B2 | Phenylsulfoxyoxazole compound inhibitors of urea transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008061248-A2 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305105-A1 | PHENYLSULFOXYOXAZOLE COMPOUND INHIBITORS OF UREA TRANSPORTERS | SLC14A1, SLCO4C1, SLCO2B1 | TP53 3827/4885ALDH1A1 2350/4885MEN1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.