Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371389 | 0.78 | ESR2 (0.41) | CYP2A6ESR2ALDH1A1HPGDTSHR | |
| SCHEMBL8734269 | 0.76 | ACHE (0.41) | HPGDTSHRSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL7704868 | 0.75 | GSTP1 (0.49) | GSTP1TSHRSMN1; SMN2 | |
| SCHEMBL5795387 | 0.74 | ACHE (0.36) | TDP1ALDH1A1CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL3193310 | 0.73 | GSTP1 (0.64) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL4280336 | 0.73 | HSD17B2 (0.45) | ESR2ESR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30491158 | 0.73 | GSTP1 (0.70) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL28508645 | 0.73 | GSTP1 (0.70) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL3155647 | 0.72 | CTSD (0.59) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL27843641 | 0.72 | GSTP1 (0.52) | GSTP1HDAC4HDAC2HDAC8CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |