Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371389 | 0.83 | ESR2 (0.41) | TSHRSMN1; SMN2PTGS2 | |
| SCHEMBL7704625 | 0.76 | ALDH1A1 (0.37) | MAOAMAOB | |
| SCHEMBL7700044 | 0.76 | GSTP1 (0.49) | GSTP1LTA4HTSHRMAOANR1H2 | |
| SCHEMBL5795387 | 0.75 | ACHE (0.36) | HTTSMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL7699446 | 0.75 | GSTP1 (0.50) | GSTP1TSHRSMN1; SMN2 | |
| SCHEMBL7704874 | 0.73 | GSTP1 (0.48) | GSTP1LTA4HTSHRMAOANR1H2 | |
| SCHEMBL197414 | 0.70 | LTA4H (0.75) | GSTP1LTA4HTSHRMAOANR1H2 | |
| SCHEMBL6406035 | 0.70 | LTA4H (0.75) | GSTP1LTA4HTSHRMAOANR1H2 | |
| SCHEMBL2860844 | 0.70 | LTA4H (0.75) | GSTP1LTA4HTSHRMAOANR1H2 | |
| SCHEMBL16398888 | 0.69 | GSTP1 (0.53) | GSTP1LTA4HTSHRMAOANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |