Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701233 | 0.89 | DYRK1A (0.51) | LRRK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7699518 | 0.86 | KDM4E (0.57) | LRRK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7701567 | 0.80 | LRRK2 (0.50) | LRRK2KDM4EALDH1A1GAAGLA | |
| SCHEMBL7698547 | 0.80 | LRRK2 (0.56) | LRRK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7695186 | 0.78 | MAP4K4 (0.42) | LRRK2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7700326 | 0.77 | LRRK2 (0.52) | LRRK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8991109 | 0.77 | KDM4E (0.59) | LRRK2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8991072 | 0.76 | LRRK2 (0.51) | LRRK2KDM4EALDH1A1GAAGLA | |
| SCHEMBL7701231 | 0.76 | DYRK1A (0.55) | LRRK2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7696582 | 0.75 | DYRK1A (0.57) | LRRK2KDM4EDYRK1AKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |