Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699520 | 0.89 | LRRK2 (0.49) | DYRK1ALRRK2ADORA2AADORA1RIPK1 | |
| SCHEMBL7701231 | 0.87 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7696582 | 0.87 | DYRK1A (0.57) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7701581 | 0.81 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL7697867 | 0.78 | DYRK1A (0.54) | DYRK1ALRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL8991102 | 0.78 | DYRK1A (0.56) | DYRK1ALRRK2ADORA2AADORA1PI4KA | |
| SCHEMBL7701084 | 0.77 | DYRK1A (0.53) | DYRK1ALRRK2ADORA2AADORA1RIPK1 | |
| SCHEMBL7698530 | 0.77 | DYRK1A (0.50) | DYRK1ALRRK2ADORA2AADORA1RIPK1 | |
| SCHEMBL7695186 | 0.77 | MAP4K4 (0.42) | LRRK2ADORA2ARIPK1PI4KAPI4K2B | |
| SCHEMBL7700915 | 0.76 | DYRK1A (0.50) | DYRK1ALRRK2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |