Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 7/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701973 | 0.93 | ADORA2A (0.54) | ABCC1LRRK2ADORA2AIGF1RSRC | |
| SCHEMBL7700385 | 0.85 | ADORA2A (0.52) | ABCC1LRRK2ADORA2AABCB1ABCG2 | |
| SCHEMBL7695185 | 0.81 | ADORA2A (0.41) | ABCC1LRRK2ADORA2ASRCKDM4E | |
| SCHEMBL7696326 | 0.80 | LRRK2 (0.44) | LRRK2ADORA2AIGF1RSRCKDM4E | |
| SCHEMBL7695186 | 0.80 | MAP4K4 (0.42) | LRRK2ADORA2AIGF1RSRCPIK3CD | |
| SCHEMBL7701585 | 0.78 | ADRA1D (0.48) | ADORA2AIGF1RSRCLCKTEK | |
| SCHEMBL7698547 | 0.76 | LRRK2 (0.56) | LRRK2ADORA2AKDM4EALDH1A1GAA | |
| SCHEMBL7695786 | 0.75 | PIK3CD (0.47) | LRRK2IGF1RSRCKDM4EALDH1A1 | |
| SCHEMBL18520393 | 0.75 | ADK (0.49) | LRRK2ADORA2AIGF1RSRCLCK | |
| SCHEMBL7699582 | 0.75 | LRRK2 (0.43) | ABCC1LRRK2ADORA2AIGF1RSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |