Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700930 | 0.88 | MAPT (0.46) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7698564 | 0.87 | ADK (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7701973 | 0.87 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7700864 | 0.87 | CFD (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7703250 | 0.86 | CFD (0.42) | ADORA2API4KBRETTSHRKDM4E | |
| SCHEMBL7699602 | 0.85 | ABCC1 (0.48) | ADORA2ATSHRKDM4EMAPK1HTT | |
| SCHEMBL7696329 | 0.84 | ADK (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7701968 | 0.84 | RIPK2 (0.45) | PI4KBCFDSRCADKPIK3CD | |
| SCHEMBL7696326 | 0.84 | LRRK2 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7702542 | 0.83 | CFD (0.43) | ADORA2ATSHRKDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |