Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SI | P14410 | 3/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697561 | 0.90 | POLB (0.54) | RAB9ATSHRMAPK1POLBIKBKB | |
| SCHEMBL7700838 | 0.89 | RAB9A (0.55) | RAB9ATSHRMAPK1POLBIKBKB | |
| SCHEMBL7699946 | 0.87 | AGER (0.55) | RAB9ATSHRMAPK1POLBIKBKB | |
| SCHEMBL7695239 | 0.85 | MAPT (0.55) | RAB9ATSHRMAPK1POLBIKBKB | |
| SCHEMBL7702798 | 0.81 | MAPT (0.50) | RAB9AMAPK1IKBKBRXFP1GAA | |
| Hydrochloric Acid SCHEMBL7992218 | 0.80 | AURKA (0.47) | RAB9ATSHRMAPK1POLBRXFP1 | |
| SCHEMBL7697491 | 0.80 | HDAC4 (0.49) | IKBKBRXFP1MAPT | |
| SCHEMBL7699301 | 0.79 | MAPT (0.53) | IKBKBRXFP1ALDH1A1LMNAHPGD | |
| SCHEMBL7693990 | 0.78 | IKBKB (0.53) | RAB9ATSHRIKBKBRXFP1ALDH1A1 | |
| SCHEMBL7699046 | 0.78 | POLB (0.45) | RAB9ATSHRPOLBIKBKBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |