Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702798 | 0.90 | MAPT (0.50) | MAPTRXFP1IKBKBHDAC4THRB | |
| SCHEMBL7693950 | 0.90 | IKBKB (0.52) | MAPTIKBKBTP53HDAC6HDAC3 | |
| SCHEMBL7697491 | 0.89 | HDAC4 (0.49) | MAPTRXFP1IKBKBHDAC4 | |
| SCHEMBL7701281 | 0.81 | MAPT (0.49) | MAPTRXFP1IKBKBHDAC4THRB | |
| SCHEMBL7701056 | 0.81 | MAPT (0.47) | MAPTRXFP1IKBKBTP53KDM4E | |
| SCHEMBL7693990 | 0.80 | IKBKB (0.53) | MAPTRXFP1IKBKBHDAC6HDAC3 | |
| SCHEMBL7703333 | 0.80 | KDM4E (0.64) | MAPTIKBKBTP53HDAC1KDM4E | |
| SCHEMBL7699046 | 0.80 | POLB (0.45) | MAPTRXFP1IKBKBTP53KDM4E | |
| SCHEMBL7699232 | 0.80 | ALDH1A1 (0.47) | MAPTRXFP1IKBKBTP53KDM4E | |
| SCHEMBL7699732 | 0.79 | RAB9A (0.53) | MAPTRXFP1IKBKBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |