Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700173 | 1.00 | SLC6A9 (0.58) | SLC6A9GRIN2BGRIN1NPY5RADRA1D | |
| SCHEMBL7700176 | 1.00 | SLC6A9 (0.58) | SLC6A9GRIN2BGRIN1NPY5RADRA1D | |
| SCHEMBL7703443 | 0.88 | BCHE (0.51) | SLC6A9GRIN2BGRIN1ADRA1DADRA1A | |
| SCHEMBL7701272 | 0.88 | BCHE (0.51) | SLC6A9GRIN2BGRIN1ADRA1DADRA1A | |
| SCHEMBL7703433 | 0.88 | BCHE (0.51) | SLC6A9GRIN2BGRIN1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7705416 | 0.85 | SLC6A9 (0.66) | SLC6A9GRIN2BGRIN1NPY5RMTNR1A | |
| SCHEMBL7703316 | 0.84 | ALDH1A1 (0.47) | GRIN2BMTNR1AMTNR1B | |
| SCHEMBL7700454 | 0.84 | MTNR1A (0.42) | SLC6A9GRIN2BGRIN1ADRA1DADRA1A | |
| SCHEMBL7706107 | 0.84 | MTNR1A (0.42) | SLC6A9GRIN2BGRIN1ADRA1DADRA1A | |
| SCHEMBL7702709 | 0.84 | ALDH1A1 (0.47) | GRIN2BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |