Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701272 | 1.00 | BCHE (0.51) | BCHEGRIN1GRIN2BHTR6SLC6A9 | |
| SCHEMBL7703443 | 1.00 | BCHE (0.51) | BCHEGRIN1GRIN2BHTR6SLC6A9 | |
| SCHEMBL7700178 | 0.88 | SLC6A9 (0.58) | BCHEGRIN1GRIN2BSLC6A9ADRA1D | |
| SCHEMBL7700173 | 0.88 | SLC6A9 (0.58) | BCHEGRIN1GRIN2BSLC6A9ADRA1D | |
| SCHEMBL7700176 | 0.88 | SLC6A9 (0.58) | BCHEGRIN1GRIN2BSLC6A9ADRA1D | |
| Hydrochloric Acid SCHEMBL7702776 | 0.85 | SLC6A9 (0.52) | GRIN1GRIN2BSLC6A9 | |
| SCHEMBL7702709 | 0.85 | ALDH1A1 (0.47) | GRIN2BSLC2A1 | |
| SCHEMBL7703309 | 0.85 | ALDH1A1 (0.47) | GRIN2BSLC2A1 | |
| SCHEMBL7703316 | 0.85 | ALDH1A1 (0.47) | GRIN2BSLC2A1 | |
| SCHEMBL7700454 | 0.83 | MTNR1A (0.42) | GRIN1GRIN2BSLC6A9ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |