Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990926 | 0.88 | EGFR (0.32) | EGFRSRCADKP2RY1YTHDC1 | |
| SCHEMBL7699595 | 0.87 | ADK (0.33) | EGFRSRCADKNPC1GALR3 | |
| SCHEMBL8991365 | 0.85 | ADORA2A (0.41) | EGFRSRCADKNPC1MAPT | |
| SCHEMBL7700980 | 0.84 | NPC1 (0.45) | EGFRSRCADKNPC1GALR3 | |
| SCHEMBL7700322 | 0.78 | ADK (0.33) | EGFRSRCADKP2RY1 | |
| SCHEMBL8990936 | 0.78 | ADK (0.33) | EGFRSRCADKALDH1A1P2RY1 | |
| SCHEMBL8991103 | 0.78 | PDE4A (0.50) | EGFRSRCNPC1ALDH1A1MAPT | |
| SCHEMBL8991231 | 0.77 | GAA (0.41) | EGFRSRCNPC1GALR3ALDH1A1 | |
| SCHEMBL8991004 | 0.76 | YTHDC1 (0.31) | EGFRSRCYTHDC1 | |
| SCHEMBL8991249 | 0.76 | ADK (0.33) | EGFRSRCADKP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |