Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699597 | 0.88 | ADK (0.35) | ADKP2RY1FLT3 | |
| SCHEMBL8991378 | 0.86 | ADORA2A (0.41) | ADKEGFRSRCPDE4APDE4B | |
| SCHEMBL7700982 | 0.85 | FLT3 (0.37) | ADKFLT3EGFRSRC | |
| SCHEMBL8990936 | 0.80 | ADK (0.33) | ADKP2RY1FLT3EGFRSRC | |
| SCHEMBL8991110 | 0.79 | PDE4A (0.50) | FLT3EGFRSRCPDE4APDE4B | |
| SCHEMBL8991244 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7700319 | 0.78 | EGFR (0.32) | ADKP2RY1EGFRSRC | |
| SCHEMBL8990926 | 0.78 | EGFR (0.32) | ADKP2RY1EGFRSRC | |
| SCHEMBL8991012 | 0.78 | XDH (0.33) | XDHP2RY1 | |
| SCHEMBL8991419 | 0.77 | PDE4A (0.40) | EGFRSRCPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |