Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 15/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704452 | 0.89 | HTT (0.41) | FLT3RETPI4KAPI4K2BPI4K2A | |
| SCHEMBL8991269 | 0.89 | PI4KA (0.39) | FLT3RETPI4KAPI4K2BPI4K2A | |
| SCHEMBL7695931 | 0.87 | ADK (0.46) | FLT3ADKRETCFDPI4KB | |
| SCHEMBL7700275 | 0.85 | CFD (0.47) | FLT3ADKRETCFD | |
| SCHEMBL7701218 | 0.84 | RET (0.52) | FLT3ADKRETCFDPI4KA | |
| SCHEMBL7701895 | 0.84 | EGFR (0.45) | ADKRETCFD | |
| SCHEMBL8991275 | 0.84 | FLT3 (0.43) | FLT3RETPI4KAPI4K2BPI4K2A | |
| SCHEMBL7704457 | 0.84 | FLT3 (0.41) | FLT3RETPI4KAPI4K2BPI4K2A | |
| SCHEMBL7704315 | 0.81 | SLC29A1 (0.44) | ADKCFD | |
| SCHEMBL7695714 | 0.79 | ADRA1D (0.51) | FLT3ADKRETCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |