Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | ABL2 | P42684 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705467 | 0.89 | EGFR (0.45) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL8991089 | 0.89 | EGFR (0.45) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7695931 | 0.87 | ADK (0.46) | EGFRSRCABL1KDRADK | |
| SCHEMBL7700275 | 0.85 | CFD (0.47) | ADKRIPK2CFDRET | |
| SCHEMBL7701218 | 0.84 | RET (0.52) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7700399 | 0.84 | FLT3 (0.45) | ADKCFDRET | |
| SCHEMBL7705468 | 0.84 | EGFR (0.43) | EGFRPDE8BSRCABL1ABL2 | |
| SCHEMBL8991091 | 0.84 | EGFR (0.43) | EGFRPDE8BSRCABL1ABL2 | |
| SCHEMBL7704315 | 0.81 | SLC29A1 (0.44) | ADKCFD | |
| SCHEMBL7695714 | 0.79 | ADRA1D (0.51) | EGFRSRCABL1ABL2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |