Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 16/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702841 | 0.92 | VCP (0.42) | VCP | |
| SCHEMBL7702827 | 0.91 | VCP (0.45) | VCP | |
| SCHEMBL7704382 | 0.88 | VCP (0.37) | VCPKCNQ4KCNQ5 | |
| SCHEMBL7465214 | 0.84 | VCP (0.45) | VCPKCNQ4KCNQ5 | |
| SCHEMBL7703166 | 0.82 | VCP (0.34) | VCP | |
| SCHEMBL7703510 | 0.82 | VCP (0.41) | VCP | |
| SCHEMBL7145884 | 0.82 | KCNQ4 (0.39) | KCNQ4KCNQ5 | |
| SCHEMBL7141292 | 0.81 | MAPT (0.36) | KCNQ4KCNQ5 | |
| SCHEMBL6868921 | 0.81 | MRGPRX4 (0.39) | VCP | |
| SCHEMBL7139867 | 0.81 | KEAP1 (0.35) | KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224174-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029011-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |