Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 16/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699300 | 0.91 | VCP (0.45) | VCP | |
| SCHEMBL7702841 | 0.90 | VCP (0.42) | VCP | |
| SCHEMBL6610284 | 0.89 | VCP (0.39) | VCP | |
| SCHEMBL7700580 | 0.82 | VCP (0.40) | VCP | |
| SCHEMBL7704777 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL7704530 | 0.80 | DHODH (0.37) | — | |
| SCHEMBL7704536 | 0.80 | DHODH (0.36) | — | |
| SCHEMBL7704182 | 0.80 | CYP3A4 (0.35) | — | |
| SCHEMBL7699016 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL7698696 | 0.78 | VCP (0.41) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224174-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029011-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |