Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691817 | 0.89 | LMNA (0.34) | LTA4HDUTALDH1A1MEN1LMNA | |
| SCHEMBL431649 | 0.87 | LTA4H (0.47) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL9228586 | 0.84 | LTA4H (0.44) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL705748 | 0.83 | DUT (0.47) | LTA4HDUTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10907580 | 0.82 | LTA4H (0.43) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL17391641 | 0.82 | LTA4H (0.43) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL3713762 | 0.82 | LTA4H (0.43) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL708046 | 0.82 | DUT (0.46) | LTA4HDUTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4855961 | 0.82 | NPSR1 (0.32) | LTA4HDUTTP53ALDH1A1MAPK1 | |
| SCHEMBL4804045 | 0.82 | LTA4H (0.47) | LTA4HTSHRTP53ABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344579-B1 | REACTION OF FLUOROSILICON COMPOUND WITH REACTION OF SILICON WITH HYDROXY, ALKOXY OR ARYLOXY GROUP WITH DIFLUORODIAMINO COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1138633-A1 | PROCESS FOR PRODUCING FLUORINATED SILICON COMPOUND | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |