Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 9/20 | 0.31 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.30 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701095 | 0.83 | CA9 (0.35) | PARP1CA12CA9 | |
| SCHEMBL7701182 | 0.82 | PARP1 (0.43) | PARP1SLC9A1SLC9A5SLC9A2HTR2B | |
| SCHEMBL7702076 | 0.81 | SLC9A1 (0.38) | SLC9A1SLC9A2 | |
| Hydrochloric Acid SCHEMBL6134781 | 0.81 | SLC9A1 (0.37) | SLC9A1SLC9A2 | |
| Hydrochloric Acid SCHEMBL6135636 | 0.81 | SLC9A1 (0.37) | SLC9A1SLC9A2 | |
| SCHEMBL7697135 | 0.80 | PARP1 (0.43) | PARP1 | |
| SCHEMBL7700277 | 0.80 | SLC9A1 (0.34) | PARP1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL7700646 | 0.80 | SLC9A1 (0.33) | PARP1SLC9A1 | |
| SCHEMBL7694853 | 0.79 | PARP1 (0.34) | PARP1 | |
| SCHEMBL7378220 | 0.79 | FABP4 (0.35) | PARP1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1073650-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055690-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-04 | — | — | WO | disclosed |