Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705445 | 0.90 | DYRK1A (0.49) | DYRK1ALRRK2SLC29A1XDHKMT2A | |
| SCHEMBL7701231 | 0.84 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1 | |
| SCHEMBL7696582 | 0.84 | DYRK1A (0.57) | DYRK1ALRRK2ADORA2AADORA1KMT2A | |
| SCHEMBL7695942 | 0.81 | MEN1 (0.50) | DYRK1ALRRK2SLC29A1XDHKMT2A | |
| SCHEMBL7695831 | 0.80 | DYRK1A (0.46) | DYRK1ALRRK2ADORA2AADORA1KMT2A | |
| SCHEMBL7701581 | 0.78 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1KMT2A | |
| SCHEMBL7701233 | 0.76 | DYRK1A (0.51) | DYRK1ALRRK2ADORA2AADORA1 | |
| SCHEMBL7695781 | 0.74 | DYRK1A (0.56) | DYRK1ALRRK2ADORA2AADORA1PIK3CD | |
| SCHEMBL7699589 | 0.74 | DYRK1A (0.55) | DYRK1ALRRK2ADORA2AADORA1KMT2A | |
| SCHEMBL7702669 | 0.73 | DYRK1A (0.57) | DYRK1ALRRK2ADORA2AADORA1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |