Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695360 | 0.89 | DGAT1 (0.54) | DGAT1MAPTRXFP1NPC1RAB9A | |
| SCHEMBL7701281 | 0.85 | MAPT (0.49) | DGAT1MAPTLMNAHDAC4RXFP1 | |
| SCHEMBL7697491 | 0.85 | HDAC4 (0.49) | DGAT1MAPTHDAC4RXFP1 | |
| SCHEMBL7702049 | 0.83 | DGAT1 (0.47) | DGAT1MAPTRXFP1NPC1RAB9A | |
| SCHEMBL7698920 | 0.82 | GFER (0.52) | DGAT1MAPTLMNANPC1RAB9A | |
| SCHEMBL7696235 | 0.80 | KMT2A (0.46) | DGAT1MAPTLMNAHDAC4RXFP1 | |
| SCHEMBL7693909 | 0.79 | GAA (0.59) | DGAT1MAPTLMNANPC1RAB9A | |
| SCHEMBL7695533 | 0.77 | ADCY8 (0.47) | DGAT1MAPTHDAC4RXFP1KDM4E | |
| SCHEMBL7702798 | 0.77 | MAPT (0.50) | DGAT1MAPTLMNAHDAC4RXFP1 | |
| SCHEMBL7693843 | 0.77 | TRPV1 (0.47) | DGAT1MAPTLMNAHDAC4RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |