Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697491 | 0.92 | HDAC4 (0.49) | MAPTHDAC4RXFP1DGAT1MCHR1 | |
| SCHEMBL7702798 | 0.91 | MAPT (0.50) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7701100 | 0.85 | DGAT1 (0.51) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7696235 | 0.84 | KMT2A (0.46) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7695533 | 0.83 | ADCY8 (0.47) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7693843 | 0.82 | TRPV1 (0.47) | MAPTHDAC4RXFP1DGAT1ALDH1A1 | |
| SCHEMBL7695161 | 0.82 | IKBKB (0.50) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7699835 | 0.81 | IKBKB (0.42) | MAPTHDAC4RXFP1DGAT1KDM4E | |
| SCHEMBL7699301 | 0.81 | MAPT (0.53) | MAPTHDAC4RXFP1KDM4EALDH1A1 | |
| SCHEMBL7699148 | 0.80 | MAPT (0.48) | MAPTRXFP1DGAT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |